Afatinib vs Doxycycline

## Afatinib vs Doxycycline: Overview

This comparison examines the pharmacological differences between **Afatinib** and **Doxycycline**.

## Mechanism of Action

**Afatinib**: Irreversible covalent inhibitor of ErbB family (EGFR/HER1, HER2, HER4) tyrosine kinases.

**Doxycycline**: Inhibits bacterial protein synthesis by binding 30S ribosomal subunit.

## Pharmacokinetics

**Half-life**: Afatinib — 37 hours; Doxycycline — 18-22 hours.

## Chemical Properties

**Molecular Formula**: Afatinib — C24H25ClFN5O3; Doxycycline — C22H24N2O8.

**Molecular Weight**: Afatinib — 485.9400 g/mol; Doxycycline — 444.4350 g/mol.

**Type**: Afatinib — Small molecule; Doxycycline — Small molecule.