Amlodipine vs Simvastatin

## Amlodipine vs Simvastatin: Overview

This comparison examines the pharmacological differences between **Amlodipine** and **Simvastatin**.

## Mechanism of Action

**Amlodipine**: Dihydropyridine calcium channel blocker.

**Simvastatin**: Prodrug converted to active form that inhibits HMG-CoA reductase.

## Pharmacokinetics

**Half-life**: Amlodipine — 30-50 hours; Simvastatin — 2 hours.

## Chemical Properties

**Molecular Formula**: Amlodipine — C20H25ClN2O5; Simvastatin — C25H38O5.

**Molecular Weight**: Amlodipine — 408.8800 g/mol; Simvastatin — 418.5700 g/mol.

**Type**: Amlodipine — Small molecule; Simvastatin — Small molecule.