Aspirin vs Captopril

## Aspirin vs Captopril: Overview

This comparison examines the pharmacological differences between **Aspirin** and **Captopril**.

## Mechanism of Action

**Aspirin**: Irreversibly inhibits cyclooxygenase-1 and -2.

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

## Pharmacokinetics

**Half-life**: Aspirin — 2-3 hours; Captopril — 1.9 hours.

## Chemical Properties

**Molecular Formula**: Aspirin — C9H8O4; Captopril — C9H15NO3S.

**Molecular Weight**: Aspirin — 180.1580 g/mol; Captopril — 217.2850 g/mol.

**Type**: Aspirin — Small molecule; Captopril — Small molecule.