Aspirin vs Trimethoprim

## Aspirin vs Trimethoprim: Overview

This comparison examines the pharmacological differences between **Aspirin** and **Trimethoprim**.

## Mechanism of Action

**Aspirin**: Irreversibly inhibits cyclooxygenase-1 and -2.

**Trimethoprim**: Dihydrofolate reductase inhibitor (bacterial selective).

## Pharmacokinetics

**Half-life**: Aspirin — 2-3 hours; Trimethoprim — 8-10 hours.

## Chemical Properties

**Molecular Formula**: Aspirin — C9H8O4; Trimethoprim — C14H18N4O3.

**Molecular Weight**: Aspirin — 180.1580 g/mol; Trimethoprim — 290.3180 g/mol.

**Type**: Aspirin — Small molecule; Trimethoprim — Small molecule.