Atenolol vs Hydrochlorothiazide

## Atenolol vs Hydrochlorothiazide: Overview

This comparison examines the pharmacological differences between **Atenolol** and **Hydrochlorothiazide**.

## Mechanism of Action

**Atenolol**: Cardioselective beta-1 adrenergic receptor blocker without intrinsic sympathomimetic activity.

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

## Pharmacokinetics

**Half-life**: Atenolol — 6-7 hours; Hydrochlorothiazide — 6-15 hours.

## Chemical Properties

**Molecular Formula**: Atenolol — C14H22N2O3; Hydrochlorothiazide — C7H8ClN3O4S2.

**Molecular Weight**: Atenolol — 266.3360 g/mol; Hydrochlorothiazide — 297.7400 g/mol.

**Type**: Atenolol — Small molecule; Hydrochlorothiazide — Small molecule.