Captopril vs Diltiazem

## Captopril vs Diltiazem: Overview

This comparison examines the pharmacological differences between **Captopril** and **Diltiazem**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Diltiazem**: Benzothiazepine calcium channel blocker.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Diltiazem — 3-4.5 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Diltiazem — C22H26N2O4S.

**Molecular Weight**: Captopril — 217.2850 g/mol; Diltiazem — 414.5190 g/mol.

**Type**: Captopril — Small molecule; Diltiazem — Small molecule.