Captopril vs Durvalumab

## Captopril vs Durvalumab: Overview

This comparison examines the pharmacological differences between **Captopril** and **Durvalumab**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Durvalumab**: Human IgG1 kappa anti-PD-L1 monoclonal antibody blocking PD-L1 binding to PD-1 and CD80.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Durvalumab — 17 days.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Durvalumab — N/A.

**Molecular Weight**: Captopril — 217.2850 g/mol; Durvalumab — N/A.

**Type**: Captopril — Small molecule; Durvalumab — Antibody.