Captopril vs Gefitinib

## Captopril vs Gefitinib: Overview

This comparison examines the pharmacological differences between **Captopril** and **Gefitinib**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Gefitinib**: Selective reversible inhibitor of EGFR tyrosine kinase.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Gefitinib — 48 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Gefitinib — C22H24ClFN4O3.

**Molecular Weight**: Captopril — 217.2850 g/mol; Gefitinib — 446.9000 g/mol.

**Type**: Captopril — Small molecule; Gefitinib — Small molecule.