Celecoxib vs Sitagliptin

## Celecoxib vs Sitagliptin: Overview

This comparison examines the pharmacological differences between **Celecoxib** and **Sitagliptin**.

## Mechanism of Action

**Celecoxib**: Selective COX-2 inhibitor.

**Sitagliptin**: DPP-4 inhibitor increasing incretin levels.

## Pharmacokinetics

**Half-life**: Celecoxib — 11 hours; Sitagliptin — 12.4 hours.

## Chemical Properties

**Molecular Formula**: Celecoxib — C17H14F3N3O2S; Sitagliptin — C16H15F6N5O.

**Molecular Weight**: Celecoxib — 381.3730 g/mol; Sitagliptin — 407.3140 g/mol.

**Type**: Celecoxib — Small molecule; Sitagliptin — Small molecule.