Celecoxib vs Tacrolimus

## Celecoxib vs Tacrolimus: Overview

This comparison examines the pharmacological differences between **Celecoxib** and **Tacrolimus**.

## Mechanism of Action

**Celecoxib**: Selective COX-2 inhibitor.

**Tacrolimus**: Calcineurin inhibitor binding FKBP12; suppresses IL-2 transcription.

## Pharmacokinetics

**Half-life**: Celecoxib — 11 hours; Tacrolimus — 12 hours.

## Chemical Properties

**Molecular Formula**: Celecoxib — C17H14F3N3O2S; Tacrolimus — C44H69NO12.

**Molecular Weight**: Celecoxib — 381.3730 g/mol; Tacrolimus — 804.0180 g/mol.

**Type**: Celecoxib — Small molecule; Tacrolimus — Small molecule.