Cetirizine vs Sitagliptin

## Cetirizine vs Sitagliptin: Overview

This comparison examines the pharmacological differences between **Cetirizine** and **Sitagliptin**.

## Mechanism of Action

**Cetirizine**: Second-generation H1 antihistamine.

**Sitagliptin**: DPP-4 inhibitor increasing incretin levels.

## Pharmacokinetics

**Half-life**: Cetirizine — 6.5-10 hours; Sitagliptin — 12.4 hours.

## Chemical Properties

**Molecular Formula**: Cetirizine — C21H25ClN2O3; Sitagliptin — C16H15F6N5O.

**Molecular Weight**: Cetirizine — 388.8900 g/mol; Sitagliptin — 407.3140 g/mol.

**Type**: Cetirizine — Small molecule; Sitagliptin — Small molecule.