Citalopram vs Sacubitril-Valsartan

## Citalopram vs Sacubitril-Valsartan: Overview

This comparison examines the pharmacological differences between **Citalopram** and **Sacubitril-Valsartan**.

## Mechanism of Action

**Citalopram**: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

**Sacubitril-Valsartan**: Angiotensin receptor-neprilysin inhibitor (ARNI) combining neprilysin inhibition with AT1 receptor blockade.

## Pharmacokinetics

**Half-life**: Citalopram — 35 hours; Sacubitril-Valsartan — 11.5 hours.

## Chemical Properties

**Molecular Formula**: Citalopram — C20H21FN2O; Sacubitril-Valsartan — C24H29N2O5.

**Molecular Weight**: Citalopram — 324.3920 g/mol; Sacubitril-Valsartan — 414.5010 g/mol.

**Type**: Citalopram — Small molecule; Sacubitril-Valsartan — Small molecule.