Hydrochlorothiazide vs Prednisone

## Hydrochlorothiazide vs Prednisone: Overview

This comparison examines the pharmacological differences between **Hydrochlorothiazide** and **Prednisone**.

## Mechanism of Action

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

**Prednisone**: Synthetic corticosteroid; suppresses inflammation via glucocorticoid receptor.

## Pharmacokinetics

**Half-life**: Hydrochlorothiazide — 6-15 hours; Prednisone — 2-3 hours.

## Chemical Properties

**Molecular Formula**: Hydrochlorothiazide — C7H8ClN3O4S2; Prednisone — C21H26O5.

**Molecular Weight**: Hydrochlorothiazide — 297.7400 g/mol; Prednisone — 358.4280 g/mol.

**Type**: Hydrochlorothiazide — Small molecule; Prednisone — Small molecule.