Losartan vs Sitagliptin

## Losartan vs Sitagliptin: Overview

This comparison examines the pharmacological differences between **Losartan** and **Sitagliptin**.

## Mechanism of Action

**Losartan**: Angiotensin II receptor type 1 antagonist.

**Sitagliptin**: DPP-4 inhibitor increasing incretin levels.

## Pharmacokinetics

**Half-life**: Losartan — 2 hours; Sitagliptin — 12.4 hours.

## Chemical Properties

**Molecular Formula**: Losartan — C22H23ClN6O; Sitagliptin — C16H15F6N5O.

**Molecular Weight**: Losartan — 422.9200 g/mol; Sitagliptin — 407.3140 g/mol.

**Type**: Losartan — Small molecule; Sitagliptin — Small molecule.