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Abacavir Sulfate

CHEMBL4303288 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
670.7 g/mol
LogP
—
Phase
4

The sulfate salt form of abacavir, an antiretroviral medicine used to treat HIV infection with the same mechanism and precautions as abacavir itself. It is taken orally, usually once or twice daily as part of a combination HIV therapy regimen. Patients should be screened for the HLA-B*5701 gene variant before starting treatment to avoid a potentially life-threatening hypersensitivity reaction.

Молекулярная масса

670,7000 g/mol

TPSA

287,00 Ų

Терапевтические области

Cardiovascular Disease Generalized Anxiety Disorder Infectious Disease Psoriasis Systemic Lupus Erythematosus Stroke Major Depressive Disorder Breast Cancer Gout Malaria HIV/AIDS Hepatitis C Tuberculosis

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Nc1nc(NC2CC2)c2ncn([C@H]3C=C[C@@H](CO)C3)c2n1.Nc1nc(NC2CC2)c2ncn([C@H]3C=C[C@@H](CO)C3)c2n1.O=S(=O)(O)O

                

                

                
                

                    
InChI

                    
InChI=1S/2C14H18N6O.H2O4S/c2*15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21;1-5(2,3)4/h2*1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19);(H2,1,2,3,4)/t2*8-,10+;/m11./s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C28H38N12O6S

                    

                    
                    

                        
HBD / HBA

                        
8 / 16

                    

                    
                    

                        
Вращаемые Связи

                        
8

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
47

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
The sulfate salt form of abacavir, an antiretroviral medicine used to treat HIV infection with the same mechanism and precautions as abacavir itself. It is taken orally, usually once or twice daily as part of a combination HIV therapy regimen. Patients should be screened for the HLA-B*5701 gene variant before starting treatment to avoid a potentially life-threatening hypersensitivity reaction.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Abacavir Sulfate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL4303288.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 441384.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.