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Acyclovir Sodium

CHEMBL1200380 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
247.2 g/mol
LogP
—
Phase
4

The intravenous sodium salt form of acyclovir, used in hospital settings to treat severe or life-threatening herpes virus infections, including herpes encephalitis, neonatal herpes, and severe chickenpox in immunocompromised patients. It delivers the same antiviral action as oral acyclovir but at higher concentrations achievable through the bloodstream. Adequate hydration during infusion is important to protect the kidneys from crystallization of the drug.

Молекулярная масса

247,1900 g/mol

TPSA

122,00 Ų

Терапевтические области

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Age-Related Macular Degeneration Pain Management Non-Small Cell Lung Cancer Chronic Obstructive Pulmonary Disease Schizophrenia Bipolar Disorder Melanoma Oncology Inflammatory Bowel Disease Systemic Lupus Erythematosus Multiple Sclerosis Chronic Kidney Disease Obesity Lymphoma Major Depressive Disorder Breast Cancer Chronic Pain HIV/AIDS Hepatitis C Tuberculosis Prostate Cancer Colorectal Cancer Leukemia

Механизм действия

Guanosine analogue inhibiting viral DNA polymerase.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Механизм

Guanosine analogue inhibiting viral DNA polymerase.

2D Структура

SVG PNG

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SMILES

                    
Nc1nc([O-])c2ncn(COCCO)c2n1.[Na+]

                

                

                
                

                    
InChI

                    
InChI=1S/C8H11N5O3.Na/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14;/h3,14H,1-2,4H2,(H3,9,11,12,15);/q;+1/p-1

                

                

                

                    
                    

                        
Molecular Formula

                        
C8H10N5NaO3

                    

                    
                    

                        
HBD / HBA

                        
2 / 7

                    

                    
                    

                        
Вращаемые Связи

                        
4

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
17

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
The intravenous sodium salt form of acyclovir, used in hospital settings to treat severe or life-threatening herpes virus infections, including herpes encephalitis, neonatal herpes, and severe chickenpox in immunocompromised patients. It delivers the same antiviral action as oral acyclovir but at higher concentrations achievable through the bloodstream. Adequate hydration during infusion is important to protect the kidneys from crystallization of the drug.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Guanosine analogue inhibiting viral DNA polymerase.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Acyclovir Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200380.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 23665721.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.