Alfentanil

CHEMBL634 Phase 4 Одобрено Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

416.5 g/mol

LogP

2.2

Phase

4

A rapid-onset, short-acting opioid analgesic used primarily in anesthesia to provide pain relief and reduce the dose of general anesthetic agents needed during surgical procedures. Its fast action and quick clearance from the body make it suitable for brief procedures and for maintaining analgesia during surgery.

Молекулярная масса

416,5000 g/mol

LogP

2,20

TPSA

81,10 Å²

Правило пяти Липинского

Соответствует

Терапевтические области

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Pain Management Non-Small Cell Lung Cancer Epilepsy Migraine Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Insomnia Chronic Kidney Disease Obesity Hypertension Breast Cancer Chronic Pain Heart Failure Prostate Cancer Colorectal Cancer

Механизм действия

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Механизм

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission …

2D Структура

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SMILES

CCC(=O)N(c1ccccc1)C1(COC)CCN(CCn2nnn(CC)c2=O)CC1

InChI

InChI=1S/C21H32N6O3/c1-4-19(28)27(18-9-7-6-8-10-18)21(17-30-3)11-13-24(14-12-21)15-16-26-20(29)25(5-2)22-23-26/h6-10H,4-5,11-17H2,1-3H3

Molecular Formula

C21H32N6O3

HBD / HBA

- / 6

Вращаемые Связи

9

Тяжёлые Атомы

30

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Часто задаваемые вопросы

A rapid-onset, short-acting opioid analgesic used primarily in anesthesia to provide pain relief and reduce the dose of general anesthetic agents needed during surgical procedures. Its fast action and quick clearance from the body make it suitable for brief procedures and for maintaining analgesia during surgery.

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Yes, Alfentanil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL634. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 51263. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Структура

Краткие Данные

Формула: C21H32N6O3
Синонимы: 1

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Медицинский отказ от ответственности

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.