Amantadine Hydrochloride

CHEMBL1569 Phase 4 Одобрено Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

187.7 g/mol

LogP

—

Phase

4

The hydrochloride salt form of amantadine, providing the same antiviral activity against influenza A and dopaminergic effects useful in Parkinson's disease and drug-induced movement disorders. This commonly used salt form is well-absorbed orally and excreted unchanged by the kidneys, requiring dose adjustment in patients with reduced kidney function.

Молекулярная масса

187,7100 g/mol

TPSA

26,00 Å²

Терапевтические области

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Glaucoma Respiratory Disease Pain Management Non-Small Cell Lung Cancer Osteoporosis Asthma Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Epilepsy Migraine Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Melanoma Oncology Systemic Lupus Erythematosus Multiple Sclerosis Stroke Type 2 Diabetes Major Depressive Disorder Breast Cancer Chronic Pain Hepatitis C Prostate Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

SVG PNG

Cite this structure

Embed this structure

SMILES

Cl.NC12CC3CC(CC(C3)C1)C2

InChI

InChI=1S/C10H17N.ClH/c11-10-4-7-1-8(5-10)3-9(2-7)6-10;/h7-9H,1-6,11H2;1H

Molecular Formula

C10H18ClN

HBD / HBA

2 / 1

Вращаемые Связи

0

Тяжёлые Атомы

12

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Часто задаваемые вопросы

The hydrochloride salt form of amantadine, providing the same antiviral activity against influenza A and dopaminergic effects useful in Parkinson's disease and drug-induced movement disorders. This commonly used salt form is well-absorbed orally and excreted unchanged by the kidneys, requiring dose adjustment in patients with reduced kidney function.

Yes, Amantadine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1569. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 64150. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Структура

Краткие Данные

Формула: C10H18ClN
Синонимы: 1

Внешние ссылки

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.