Ampicillin Sodium

CHEMBL1200758 Phase 4 Одобрено Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

371.4 g/mol

LogP

—

Phase

4

The sodium salt form of ampicillin used for intravenous and intramuscular injection, providing rapid delivery of this beta-lactam antibiotic in hospital settings. It works by the same cell-wall disruption mechanism as oral ampicillin.

Молекулярная масса

371,4000 g/mol

TPSA

141,00 Å²

Терапевтические области

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Cardiovascular Disease Age-Related Macular Degeneration Respiratory Disease Pain Management Non-Small Cell Lung Cancer Asthma Chronic Obstructive Pulmonary Disease Parkinson's Disease Epilepsy Migraine Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Insomnia Infectious Disease Gastroesophageal Reflux Disease Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Obesity Lymphoma Type 2 Diabetes Hypertension Breast Cancer Chronic Pain Malaria HIV/AIDS Tuberculosis Heart Failure Prostate Cancer Colorectal Cancer Leukemia

Механизм действия

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), preventing transpeptidation and cross-linking of peptidoglycan chains. This weakens the bacterial cell wall, leading to osmotic lysis and cell death.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Механизм

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), preventing transpeptidation and cross-linking of peptidoglycan chains. This weakens the bacterial cell wall, leading to osmotic lysis and cell …

2D Структура

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SMILES

CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(=O)[O-].[Na+]

InChI

InChI=1S/C16H19N3O4S.Na/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);/q;+1/p-1/t9-,10-,11+,14-;/m1./s1

Molecular Formula

C16H18N3NaO4S

HBD / HBA

2 / 6

Вращаемые Связи

4

Тяжёлые Атомы

25

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Часто задаваемые вопросы

The sodium salt form of ampicillin used for intravenous and intramuscular injection, providing rapid delivery of this beta-lactam antibiotic in hospital settings. It works by the same cell-wall disruption mechanism as oral ampicillin.

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), preventing transpeptidation and cross-linking of peptidoglycan chains. This weakens the bacterial cell wall, leading to osmotic lysis and cell death.

Yes, Ampicillin Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200758. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 23663979. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Структура

Краткие Данные

Формула: C16H18N3NaO4S
Синонимы: 4

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Медицинский отказ от ответственности

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.