Bepridil
A calcium channel blocker that was used to treat chronic stable angina and certain heart arrhythmias. It works by slowing electrical conduction in the heart and relaxing blood vessels. Due to serious cardiac side effects, including potentially fatal arrhythmias, its use was discontinued in many countries.
Молекулярная масса
366,5000 g/mol
LogP
5,30
TPSA
15,70 Ų
Правило пяти Липинского
Соответствует
Терапевтические области
Механизм действия
Blocks L-type voltage-gated calcium channels in vascular smooth muscle and cardiac myocytes, reducing calcium influx during depolarization. This produces vasodilation, decreased myocardial contractility, and reduced heart rate.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Blocks L-type voltage-gated calcium channels in vascular smooth muscle and cardiac myocytes, reducing calcium influx during depolarization. This produces vasodilation, decreased myocardial contractility, and reduced heart rate.
2D Структура
Cite this structure
Embed this structure
SMILES
CC(C)COCC(CN(Cc1ccccc1)c1ccccc1)N1CCCC1
InChI
InChI=1S/C24H34N2O/c1-21(2)19-27-20-24(25-15-9-10-16-25)18-26(23-13-7-4-8-14-23)17-22-11-5-3-6-12-22/h3-8,11-14,21,24H,9-10,15-20H2,1-2H3
Molecular Formula
C24H34N2O
HBD / HBA
- / 3
Вращаемые Связи
10
Тяжёлые Атомы
27
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Часто задаваемые вопросы
A calcium channel blocker that was used to treat chronic stable angina and certain heart arrhythmias. It works by slowing electrical conduction in the heart and relaxing blood vessels. Due to serious cardiac side effects, including potentially fatal arrhythmias, its use was discontinued in many countries.
Blocks L-type voltage-gated calcium channels in vascular smooth muscle and cardiac myocytes, reducing calcium influx during depolarization. This produces vasodilation, decreased myocardial contractility, and reduced heart rate.
Yes, Bepridil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1008. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 2351. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Медицинский отказ от ответственности
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="bepridil"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/bepridil/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/bepridil/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/bepridil/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="bepridil"></drugfyi-drug>