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Bretylium

CHEMBL1199080 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
243.2 g/mol
LogP
2.8
Phase
4

An older antiarrhythmic medication that was used to treat life-threatening ventricular arrhythmias, including ventricular fibrillation, primarily in emergency settings. It works by blocking the release of norepinephrine from sympathetic nerve endings. It has largely been replaced by more effective and better-studied agents in advanced cardiac life support.

Молекулярная масса

243,1600 g/mol

LogP

2,80

TPSA

0,00 Ų

Правило пяти Липинского

Соответствует

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

SVG PNG

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SMILES

                    
CC[N+](C)(C)Cc1ccccc1Br

                

                

                
                

                    
InChI

                    
InChI=1S/C11H17BrN/c1-4-13(2,3)9-10-7-5-6-8-11(10)12/h5-8H,4,9H2,1-3H3/q+1

                

                

                

                    
                    

                        
Molecular Formula

                        
C11H17BrN+

                    

                    
                    

                        
HBD / HBA

                        
- / -

                    

                    
                    

                        
Вращаемые Связи

                        
3

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
13

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
An older antiarrhythmic medication that was used to treat life-threatening ventricular arrhythmias, including ventricular fibrillation, primarily in emergency settings. It works by blocking the release of norepinephrine from sympathetic nerve endings. It has largely been replaced by more effective and better-studied agents in advanced cardiac life support.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Bretylium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1199080.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 2431.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.