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Brivaracetam

CHEMBL607400 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
212.3 g/mol
LogP
1.0
Phase
4

An anticonvulsant medication used as adjunctive therapy in adults and children with focal-onset seizures. It binds to a specific protein in nerve terminals called SV2A to modulate neurotransmitter release and reduce excessive neuronal firing. It has a rapid onset of action and is available in both oral and intravenous formulations.

Молекулярная масса

212,2900 g/mol

LogP

1,00

TPSA

63,40 Ų

Правило пяти Липинского

Соответствует

Терапевтические области

Epilepsy

Механизм действия

Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of seizure activity.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Механизм

Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of …

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CCC[C@@H]1CC(=O)N([C@@H](CC)C(N)=O)C1

                

                

                
                

                    
InChI

                    
InChI=1S/C11H20N2O2/c1-3-5-8-6-10(14)13(7-8)9(4-2)11(12)15/h8-9H,3-7H2,1-2H3,(H2,12,15)/t8-,9+/m1/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C11H20N2O2

                    

                    
                    

                        
HBD / HBA

                        
1 / 2

                    

                    
                    

                        
Вращаемые Связи

                        
5

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
15

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
An anticonvulsant medication used as adjunctive therapy in adults and children with focal-onset seizures. It binds to a specific protein in nerve terminals called SV2A to modulate neurotransmitter release and reduce excessive neuronal firing. It has a rapid onset of action and is available in both oral and intravenous formulations.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of seizure activity.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Brivaracetam is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL607400.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 9837243.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.