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Bromfenac Sodium

CHEMBL3181947 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
766.3 g/mol
LogP
—
Phase
4

The sodium salt of bromfenac, used as ophthalmic drops to manage ocular inflammation and pain after cataract surgery. Like the base compound, it inhibits prostaglandin synthesis in the eye to reduce post-surgical swelling and discomfort. It has a relatively long duration of action due to its ability to penetrate ocular tissues.

Молекулярная масса

766,3000 g/mol

TPSA

169,00 Ų

Терапевтические области

Glaucoma Age-Related Macular Degeneration Pain Management Chronic Pain

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Nc1c(CC(=O)[O-])cccc1C(=O)c1ccc(Br)cc1.Nc1c(CC(=O)[O-])cccc1C(=O)c1ccc(Br)cc1.O.O.O.[Na+].[Na+]

                

                

                
                

                    
InChI

                    
InChI=1S/2C15H12BrNO3.2Na.3H2O/c2*16-11-6-4-9(5-7-11)15(20)12-3-1-2-10(14(12)17)8-13(18)19;;;;;/h2*1-7H,8,17H2,(H,18,19);;;3*1H2/q;;2*+1;;;/p-2

                

                

                

                    
                    

                        
Molecular Formula

                        
C30H28Br2N2Na2O9

                    

                    
                    

                        
HBD / HBA

                        
5 / 11

                    

                    
                    

                        
Вращаемые Связи

                        
6

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
45

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
The sodium salt of bromfenac, used as ophthalmic drops to manage ocular inflammation and pain after cataract surgery. Like the base compound, it inhibits prostaglandin synthesis in the eye to reduce post-surgical swelling and discomfort. It has a relatively long duration of action due to its ability to penetrate ocular tissues.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Bromfenac Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL3181947.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 11954316.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.