Calcitriol
The active hormonal form of vitamin D that regulates calcium and phosphate absorption in the intestines and controls bone metabolism. It is used to treat hypocalcemia and metabolic bone disease in patients with chronic kidney disease or hypoparathyroidism, who cannot adequately convert vitamin D to its active form. Careful dosing is required to avoid dangerously high calcium levels.
Молекулярная масса
416,6000 g/mol
LogP
5,10
TPSA
60,70 Ų
Правило пяти Липинского
Соответствует
Терапевтические области
Механизм действия
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
2D Структура
Cite this structure
Embed this structure
SMILES
C=C1/C(=C\C=C2/CCC[C@]3(C)[C@@H]([C@H](C)CCCC(C)(C)O)CC[C@@H]23)C[C@@H](O)C[C@@H]1O
InChI
InChI=1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1
Molecular Formula
C27H44O3
HBD / HBA
3 / 3
Вращаемые Связи
6
Тяжёлые Атомы
30
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Часто задаваемые вопросы
The active hormonal form of vitamin D that regulates calcium and phosphate absorption in the intestines and controls bone metabolism. It is used to treat hypocalcemia and metabolic bone disease in patients with chronic kidney disease or hypoparathyroidism, who cannot adequately convert vitamin D to its active form. Careful dosing is required to avoid dangerously high calcium levels.
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Yes, Calcitriol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL846. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5280453. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Медицинский отказ от ответственности
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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