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Candesartan

Phase 4 Одобрено Small molecule
Half-Life
9 hours
Bioavailability
—
Protein Binding
—
Molecular Weight
610.7 g/mol
LogP
4.1
Phase
4

An angiotensin II receptor blocker used to treat high blood pressure and heart failure. By blocking the angiotensin II receptor, it dilates blood vessels and reduces the workload on the heart. It is also used to protect kidney function in patients with type 2 diabetes and high blood pressure.

Молекулярная масса

610,6640 g/mol

LogP

4,10

TPSA

119,00 Ų

Правило пяти Липинского

Соответствует

Терапевтические области

Ovarian Cancer Cardiovascular Disease Rheumatoid Arthritis Migraine Bipolar Disorder Chronic Kidney Disease Stroke Hyperlipidemia Obesity Type 2 Diabetes Hypertension Breast Cancer Hepatitis C Heart Failure Atrial Fibrillation

Классы препаратов

C — C - Cardiovascular System

Механизм действия

Prodrug hydrolyzed to active form; selective angiotensin II type 1 receptor blocker.

Pharmacokinetics (PK)

Half-Life 9 hours

Pharmacodynamics (PD)

Механизм

Prodrug hydrolyzed to active form; selective angiotensin II type 1 receptor blocker.

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C24H20N6O3/c1-2-33-24-25-20-9-5-8-19(23(31)32)21(20)30(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29)

                

                

                

                    
                    

                        
Molecular Formula

                        
C33H34N6O6

                    

                    
                    

                        
HBD / HBA

                        
2 / 7

                    

                    
                    

                        
Вращаемые Связи

                        
7

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
33

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
An angiotensin II receptor blocker used to treat high blood pressure and heart failure. By blocking the angiotensin II receptor, it dilates blood vessels and reduces the workload on the heart. It is also used to protect kidney function in patients with type 2 diabetes and high blood pressure.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Prodrug hydrolyzed to active form; selective angiotensin II type 1 receptor blocker.

                        

                    

                    

                    
                    

                        
                        

                            
Key pharmacokinetic parameters for Candesartan: Half-life: 9 hours.

                        

                    

                    

                    

                        
                        

                            
Yes, Candesartan is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            
            

                
Related Drugs


                
                

                    
Same Drug Class

                    

                        
                        
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                            Small molecule
                        
                        
                        
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                            Metoprolol
                            Small molecule
                        
                        
                    

                

                

                
            

            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
        
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                PubChem — National Center for Biotechnology Information (NCBI).
                CID 2541.
                Chemical information database.
            
        
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Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.