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Flosequinan

CHEMBL1908307 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
239.3 g/mol
LogP
1.1
Phase
4

A vasodilator formerly investigated for the treatment of heart failure that works by relaxing blood vessels to reduce the workload on the heart. It was withdrawn from the market due to concerns about increased mortality with long-term use. Research into its mechanism contributed to the understanding of heart failure pharmacology.

Молекулярная масса

239,2700 g/mol

LogP

1,10

TPSA

56,60 Ų

Правило пяти Липинского

Соответствует

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Cn1cc([S+](C)[O-])c(=O)c2ccc(F)cc21

                

                

                
                

                    
InChI

                    
InChI=1S/C11H10FNO2S/c1-13-6-10(16(2)15)11(14)8-4-3-7(12)5-9(8)13/h3-6H,1-2H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C11H10FNO2S

                    

                    
                    

                        
HBD / HBA

                        
- / 5

                    

                    
                    

                        
Вращаемые Связи

                        
1

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
16

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
A vasodilator formerly investigated for the treatment of heart failure that works by relaxing blood vessels to reduce the workload on the heart. It was withdrawn from the market due to concerns about increased mortality with long-term use. Research into its mechanism contributed to the understanding of heart failure pharmacology.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Flosequinan is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1908307.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4474062.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.