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Fosdenopterin

CHEMBL2338675 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
363.2 g/mol
LogP
-4.0
Phase
4

This medication is used to treat molybdenum cofactor deficiency type A, an extremely rare and severe genetic disorder that affects the brain due to the buildup of toxic sulfite. It works as a replacement for cyclic pyranopterin monophosphate (cPMP), a precursor that the body cannot produce on its own. Treatment must begin very early in life to prevent irreversible neurological damage.

Молекулярная масса

363,2200 g/mol

LogP

-4,00

TPSA

197,00 Ų

Правило пяти Липинского

Не соответствует

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

SVG PNG

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SMILES

                    
Nc1nc(=O)c2c([nH]1)N[C@@H]1O[C@@H]3COP(=O)(O)O[C@@H]3C(O)(O)[C@@H]1N2

                

                

                
                

                    
InChI

                    
InChI=1S/C10H14N5O8P/c11-9-14-6-3(7(16)15-9)12-4-8(13-6)22-2-1-21-24(19,20)23-5(2)10(4,17)18/h2,4-5,8,12,17-18H,1H2,(H,19,20)(H4,11,13,14,15,16)/t2-,4-,5+,8-/m1/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C10H14N5O8P

                    

                    
                    

                        
HBD / HBA

                        
7 / 11

                    

                    
                    

                        
Вращаемые Связи

                        
0

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
24

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
This medication is used to treat molybdenum cofactor deficiency type A, an extremely rare and severe genetic disorder that affects the brain due to the buildup of toxic sulfite. It works as a replacement for cyclic pyranopterin monophosphate (cPMP), a precursor that the body cannot produce on its own. Treatment must begin very early in life to prevent irreversible neurological damage.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Fosdenopterin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL2338675.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 135463437.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.