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Ibuprofen Lysine

CHEMBL1201141 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
352.5 g/mol
LogP
—
Phase
4

This is the lysine salt form of ibuprofen, which may dissolve more quickly than standard ibuprofen, potentially providing faster onset of pain relief. The lysine conjugate improves the solubility of ibuprofen for certain formulations, including intravenous use for closing patent ductus arteriosus in premature infants. It shares the anti-inflammatory, analgesic, and antipyretic properties of ibuprofen.

Молекулярная масса

352,5000 g/mol

TPSA

127,00 Ų

Терапевтические области

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Benign Prostatic Hyperplasia Glaucoma Cardiovascular Disease Respiratory Disease Pain Management Non-Small Cell Lung Cancer Rheumatoid Arthritis Osteoporosis Asthma Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Epilepsy Migraine Generalized Anxiety Disorder Insomnia Infectious Disease Melanoma Gastroesophageal Reflux Disease Inflammatory Bowel Disease Obstetrics & Gynecology Multiple Sclerosis Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Urology Stroke Hyperlipidemia Obesity Lymphoma Gastroenterology Hypertension Major Depressive Disorder Breast Cancer Chronic Pain Malaria Tuberculosis Prostate Cancer Colorectal Cancer Leukemia

Механизм действия

Non-selective COX inhibitor reducing prostaglandin synthesis.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Механизм

Non-selective COX inhibitor reducing prostaglandin synthesis.

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CC(C)Cc1ccc(C(C)C(=O)O)cc1.NCCCC[C@H](N)C(=O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C13H18O2.C6H14N2O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15;7-4-2-1-3-5(8)6(9)10/h4-7,9-10H,8H2,1-3H3,(H,14,15);5H,1-4,7-8H2,(H,9,10)/t;5-/m.0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C19H32N2O4

                    

                    
                    

                        
HBD / HBA

                        
4 / 6

                    

                    
                    

                        
Вращаемые Связи

                        
9

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
25

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
This is the lysine salt form of ibuprofen, which may dissolve more quickly than standard ibuprofen, potentially providing faster onset of pain relief. The lysine conjugate improves the solubility of ibuprofen for certain formulations, including intravenous use for closing patent ductus arteriosus in premature infants. It shares the anti-inflammatory, analgesic, and antipyretic properties of ibuprofen.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Non-selective COX inhibitor reducing prostaglandin synthesis.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Ibuprofen Lysine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1201141.
                Open-access bioactivity database.
            
        
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  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 9841440.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.