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Levothyroxine Sodium

CHEMBL2103741 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
798.8 g/mol
LogP
—
Phase
4

The sodium salt form of levothyroxine, the standard pharmaceutical preparation used to treat hypothyroidism and thyroid cancer. It is the most widely prescribed form of thyroid hormone replacement therapy.

Молекулярная масса

798,8500 g/mol

TPSA

95,60 Ų

Терапевтические области

Thyroid Cancer Cardiovascular Disease Osteoporosis Asthma Schizophrenia Bipolar Disorder Systemic Lupus Erythematosus Multiple Sclerosis Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Obesity Type 2 Diabetes Breast Cancer Heart Failure Prostate Cancer

Механизм действия

Synthetic thyroid hormone T4 replacement.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Механизм

Synthetic thyroid hormone T4 replacement.

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(=O)[O-].O.[Na+]

                

                

                
                

                    
InChI

                    
InChI=1S/C15H11I4NO4.Na.H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;1H2/q;+1;/p-1/t12-;;/m0../s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C15H10I4NNaO4

                    

                    
                    

                        
HBD / HBA

                        
2 / 5

                    

                    
                    

                        
Вращаемые Связи

                        
5

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
25

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
The sodium salt form of levothyroxine, the standard pharmaceutical preparation used to treat hypothyroidism and thyroid cancer. It is the most widely prescribed form of thyroid hormone replacement therapy.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Synthetic thyroid hormone T4 replacement.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Levothyroxine Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL2103741.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 23666112.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.