Lomustine

CHEMBL514 Phase 4 Одобрено Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

233.7 g/mol

LogP

2.8

Phase

4

An alkylating chemotherapy agent used to treat brain tumors and Hodgkin's lymphoma, taken orally every six weeks. It crosses the blood-brain barrier to damage DNA in cancer cells, preventing their replication.

Молекулярная масса

233,6900 g/mol

LogP

2,80

TPSA

61,80 Å²

Правило пяти Липинского

Соответствует

Терапевтические области

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Melanoma Lymphoma Breast Cancer Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

SVG PNG

Cite this structure

Embed this structure

SMILES

O=NN(CCCl)C(=O)NC1CCCCC1

InChI

InChI=1S/C9H16ClN3O2/c10-6-7-13(12-15)9(14)11-8-4-2-1-3-5-8/h8H,1-7H2,(H,11,14)

Molecular Formula

C9H16ClN3O2

HBD / HBA

1 / 3

Вращаемые Связи

3

Тяжёлые Атомы

15

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Часто задаваемые вопросы

An alkylating chemotherapy agent used to treat brain tumors and Hodgkin's lymphoma, taken orally every six weeks. It crosses the blood-brain barrier to damage DNA in cancer cells, preventing their replication.

Yes, Lomustine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL514. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 3950. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Структура

Краткие Данные

Формула: C9H16ClN3O2
Синонимы: 2

Внешние ссылки

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Медицинский отказ от ответственности

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.