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Mephentermine

CHEMBL1201234 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
163.3 g/mol
LogP
2.4
Phase
4

This sympathomimetic amine is used in anesthesia to treat low blood pressure (hypotension) by stimulating the release of norepinephrine and directly activating adrenergic receptors to constrict blood vessels and increase cardiac output. It is particularly useful for managing the blood pressure drops that can occur during spinal or general anesthesia.

Молекулярная масса

163,2600 g/mol

LogP

2,40

TPSA

12,00 Ų

Правило пяти Липинского

Соответствует

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

SVG PNG

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SMILES

                    
CNC(C)(C)Cc1ccccc1

                

                

                
                

                    
InChI

                    
InChI=1S/C11H17N/c1-11(2,12-3)9-10-7-5-4-6-8-10/h4-8,12H,9H2,1-3H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C11H17N

                    

                    
                    

                        
HBD / HBA

                        
1 / 1

                    

                    
                    

                        
Вращаемые Связи

                        
3

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
12

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
This sympathomimetic amine is used in anesthesia to treat low blood pressure (hypotension) by stimulating the release of norepinephrine and directly activating adrenergic receptors to constrict blood vessels and increase cardiac output. It is particularly useful for managing the blood pressure drops that can occur during spinal or general anesthesia.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Mephentermine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1201234.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 3677.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.