Nelfinavir
This protease inhibitor antiviral medication is used as part of combination therapy to treat HIV infection. It works by blocking an enzyme that HIV needs to produce mature, infectious viral particles, thereby reducing the amount of virus in the body.
Молекулярная масса
567,8000 g/mol
LogP
5,70
TPSA
127,00 Ų
Правило пяти Липинского
Не соответствует
Терапевтические области
Механизм действия
Inhibits viral protease, an enzyme essential for cleaving polyprotein precursors into functional viral proteins required for viral maturation and infectivity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Inhibits viral protease, an enzyme essential for cleaving polyprotein precursors into functional viral proteins required for viral maturation and infectivity.
2D Структура
Cite this structure
Embed this structure
SMILES
Cc1c(O)cccc1C(=O)N[C@@H](CSc1ccccc1)[C@H](O)CN1C[C@H]2CCCC[C@H]2C[C@H]1C(=O)NC(C)(C)C
InChI
InChI=1S/C32H45N3O4S/c1-21-25(15-10-16-28(21)36)30(38)33-26(20-40-24-13-6-5-7-14-24)29(37)19-35-18-23-12-9-8-11-22(23)17-27(35)31(39)34-32(2,3)4/h5-7,10,13-16,22-23,26-27,29,36-37H,8-9,11-12,17-20H2,1-4H3,(H,33,38)(H,34,39)/t22-,23+,26-,27-,29+/m0/s1
Molecular Formula
C32H45N3O4S
HBD / HBA
4 / 6
Вращаемые Связи
10
Тяжёлые Атомы
40
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Часто задаваемые вопросы
This protease inhibitor antiviral medication is used as part of combination therapy to treat HIV infection. It works by blocking an enzyme that HIV needs to produce mature, infectious viral particles, thereby reducing the amount of virus in the body.
Inhibits viral protease, an enzyme essential for cleaving polyprotein precursors into functional viral proteins required for viral maturation and infectivity.
Yes, Nelfinavir is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL584. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 64143. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Медицинский отказ от ответственности
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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