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Pargyline

CHEMBL673 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
159.2 g/mol
LogP
2.1
Phase
4

A monoamine oxidase B inhibitor that was used as an antihypertensive drug but is no longer in clinical use due to its potential for serious interactions with foods and drugs. It works by inhibiting MAO-B, leading to increased levels of catecholamines in the nervous system.

Молекулярная масса

159,2300 g/mol

LogP

2,10

TPSA

3,20 Ų

Правило пяти Липинского

Соответствует

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
C#CCN(C)Cc1ccccc1

                

                

                
                

                    
InChI

                    
InChI=1S/C11H13N/c1-3-9-12(2)10-11-7-5-4-6-8-11/h1,4-8H,9-10H2,2H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C11H13N

                    

                    
                    

                        
HBD / HBA

                        
- / 1

                    

                    
                    

                        
Вращаемые Связи

                        
3

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
12

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
A monoamine oxidase B inhibitor that was used as an antihypertensive drug but is no longer in clinical use due to its potential for serious interactions with foods and drugs. It works by inhibiting MAO-B, leading to increased levels of catecholamines in the nervous system.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Pargyline is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL673.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4688.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.