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Perhexiline

CHEMBL75880 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
277.5 g/mol
LogP
6.8
Phase
4

An antianginal drug used in some countries (particularly Australia) to treat refractory angina by shifting cardiac metabolism from fatty acids to glucose, reducing oxygen demand of the heart muscle. It requires therapeutic drug monitoring due to its variable metabolism and potential for liver and peripheral nerve toxicity.

Молекулярная масса

277,5000 g/mol

LogP

6,80

TPSA

12,00 Ų

Правило пяти Липинского

Соответствует

Терапевтические области

Heart Failure

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

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SMILES

                    
C1CCC(C(CC2CCCCN2)C2CCCCC2)CC1

                

                

                
                

                    
InChI

                    
InChI=1S/C19H35N/c1-3-9-16(10-4-1)19(17-11-5-2-6-12-17)15-18-13-7-8-14-20-18/h16-20H,1-15H2

                

                

                

                    
                    

                        
Molecular Formula

                        
C19H35N

                    

                    
                    

                        
HBD / HBA

                        
1 / 1

                    

                    
                    

                        
Вращаемые Связи

                        
4

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
20

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
An antianginal drug used in some countries (particularly Australia) to treat refractory angina by shifting cardiac metabolism from fatty acids to glucose, reducing oxygen demand of the heart muscle. It requires therapeutic drug monitoring due to its variable metabolism and potential for liver and peripheral nerve toxicity.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Perhexiline is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL75880.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4746.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.