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Phenacemide

CHEMBL918 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
178.2 g/mol
LogP
0.9
Phase
4

Phenacemide is an anticonvulsant agent of the acylureide class that was historically used in the management of severe, refractory epilepsy, particularly complex partial seizures. Its mechanism involves stabilization of neuronal membranes, though its significant hepatotoxic and psychiatric side effects have led to its discontinuation in most markets.

Молекулярная масса

178,1900 g/mol

LogP

0,90

TPSA

72,20 Ų

Правило пяти Липинского

Соответствует

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
NC(=O)NC(=O)Cc1ccccc1

                

                

                
                

                    
InChI

                    
InChI=1S/C9H10N2O2/c10-9(13)11-8(12)6-7-4-2-1-3-5-7/h1-5H,6H2,(H3,10,11,12,13)

                

                

                

                    
                    

                        
Molecular Formula

                        
C9H10N2O2

                    

                    
                    

                        
HBD / HBA

                        
2 / 2

                    

                    
                    

                        
Вращаемые Связи

                        
2

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
13

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
Phenacemide is an anticonvulsant agent of the acylureide class that was historically used in the management of severe, refractory epilepsy, particularly complex partial seizures. Its mechanism involves stabilization of neuronal membranes, though its significant hepatotoxic and psychiatric side effects have led to its discontinuation in most markets.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Phenacemide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL918.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4753.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.