Phenothrin

CHEMBL1322884 Phase 4 Одобрено Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
350.4 g/mol
LogP
6.2
Phase
4

Phenothrin is a synthetic pyrethroid insecticide with antiparasitic activity that disrupts insect neuronal sodium channels, causing repetitive nerve firing, paralysis, and death of ectoparasites. It is primarily used topically for the treatment of head lice infestations and as a household insecticide.

Молекулярная масса

350,4000 g/mol

LogP

6,20

TPSA

35,50 Ų

Правило пяти Липинского

Соответствует

Механизм действия

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Механизм

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

2D Структура

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SMILES

CC(C)=CC1C(C(=O)OCc2cccc(Oc3ccccc3)c2)C1(C)C

InChI

InChI=1S/C23H26O3/c1-16(2)13-20-21(23(20,3)4)22(24)25-15-17-9-8-12-19(14-17)26-18-10-6-5-7-11-18/h5-14,20-21H,15H2,1-4H3

Molecular Formula

C23H26O3

HBD / HBA

- / 3

Вращаемые Связи

7

Тяжёлые Атомы

26

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Часто задаваемые вопросы

Phenothrin is a synthetic pyrethroid insecticide with antiparasitic activity that disrupts insect neuronal sodium channels, causing repetitive nerve firing, paralysis, and death of ectoparasites. It is primarily used topically for the treatment of head lice infestations and as a household insecticide.

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Yes, Phenothrin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1322884. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 4767. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Медицинский отказ от ответственности

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.