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Phenyl Aminosalicylate

CHEMBL1200868 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
229.2 g/mol
LogP
3.2
Phase
4

Phenyl aminosalicylate is an ester of aminosalicylic acid with anti-inflammatory and antimycobacterial properties that was used as a second-line agent in the treatment of tuberculosis. It acts by competitive inhibition of para-aminobenzoic acid incorporation into folate synthesis in mycobacteria, thereby disrupting bacterial folate metabolism.

Молекулярная масса

229,2300 g/mol

LogP

3,20

TPSA

72,60 Ų

Правило пяти Липинского

Соответствует

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Nc1ccc(C(=O)Oc2ccccc2)c(O)c1

                

                

                
                

                    
InChI

                    
InChI=1S/C13H11NO3/c14-9-6-7-11(12(15)8-9)13(16)17-10-4-2-1-3-5-10/h1-8,15H,14H2

                

                

                

                    
                    

                        
Molecular Formula

                        
C13H11NO3

                    

                    
                    

                        
HBD / HBA

                        
2 / 4

                    

                    
                    

                        
Вращаемые Связи

                        
3

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
17

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
Phenyl aminosalicylate is an ester of aminosalicylic acid with anti-inflammatory and antimycobacterial properties that was used as a second-line agent in the treatment of tuberculosis. It acts by competitive inhibition of para-aminobenzoic acid incorporation into folate synthesis in mycobacteria, thereby disrupting bacterial folate metabolism.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Phenyl Aminosalicylate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200868.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 8609.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.