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Pinacidil

CHEMBL1200338 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
263.3 g/mol
LogP
—
Phase
4

Pinacidil is a potassium channel opener of the cyanoguanidine class that activates ATP-sensitive potassium (K-ATP) channels in vascular smooth muscle, causing hyperpolarization, relaxation, and vasodilation. It was investigated as an antihypertensive agent and has been used experimentally in cardioprotection research, though it never achieved widespread clinical use.

Молекулярная масса

263,3400 g/mol

TPSA

74,10 Ų

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CC(N/C(=N\C#N)Nc1ccncc1)C(C)(C)C.O

                

                

                
                

                    
InChI

                    
InChI=1S/C13H19N5.H2O/c1-10(13(2,3)4)17-12(16-9-14)18-11-5-7-15-8-6-11;/h5-8,10H,1-4H3,(H2,15,16,17,18);1H2

                

                

                

                    
                    

                        
Molecular Formula

                        
C13H21N5O

                    

                    
                    

                        
HBD / HBA

                        
3 / 4

                    

                    
                    

                        
Вращаемые Связи

                        
5

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
19

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
Pinacidil is a potassium channel opener of the cyanoguanidine class that activates ATP-sensitive potassium (K-ATP) channels in vascular smooth muscle, causing hyperpolarization, relaxation, and vasodilation. It was investigated as an antihypertensive agent and has been used experimentally in cardioprotection research, though it never achieved widespread clinical use.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Pinacidil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
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                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200338.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 55329.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.