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Prochlorperazine

CHEMBL728 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
373.9 g/mol
LogP
4.9
Phase
4

Used to control severe nausea and vomiting caused by surgery, chemotherapy, or other conditions, and also used to treat symptoms of schizophrenia and anxiety. It works by blocking dopamine receptors in the brain regions that control nausea and psychotic symptoms.

Молекулярная масса

373,9000 g/mol

LogP

4,90

TPSA

35,00 Ų

Правило пяти Липинского

Соответствует

Терапевтические области

Ovarian Cancer Pain Management Non-Small Cell Lung Cancer Migraine Schizophrenia Lymphoma Breast Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1

                

                

                
                

                    
InChI

                    
InChI=1S/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C20H24ClN3S

                    

                    
                    

                        
HBD / HBA

                        
- / 4

                    

                    
                    

                        
Вращаемые Связи

                        
4

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
25

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
Used to control severe nausea and vomiting caused by surgery, chemotherapy, or other conditions, and also used to treat symptoms of schizophrenia and anxiety. It works by blocking dopamine receptors in the brain regions that control nausea and psychotic symptoms.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Prochlorperazine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL728.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4917.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.