Pyrithione Zinc
Pyrithione zinc is a coordination complex of zinc and pyrithione with broad-spectrum antifungal and antibacterial activity that acts by disrupting membrane proton gradients and inhibiting key metabolic enzymes in Malassezia and other microorganisms. It is widely used in over-the-counter shampoos for dandruff and seborrheic dermatitis treatment, and in topical preparations for various dermatological conditions.
Молекулярная масса
317,7000 g/mol
TPSA
52,90 Ų
Механизм действия
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
2D Структура
Cite this structure
Embed this structure
SMILES
[O-][n+]1ccccc1[S-].[O-][n+]1ccccc1[S-].[Zn+2]
InChI
InChI=1S/2C5H5NOS.Zn/c2*7-6-4-2-1-3-5(6)8;/h2*1-4,8H;/q;;+2/p-2
Molecular Formula
C10H8N2O2S2Zn
HBD / HBA
- / 4
Вращаемые Связи
2
Тяжёлые Атомы
17
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Часто задаваемые вопросы
Pyrithione zinc is a coordination complex of zinc and pyrithione with broad-spectrum antifungal and antibacterial activity that acts by disrupting membrane proton gradients and inhibiting key metabolic enzymes in Malassezia and other microorganisms. It is widely used in over-the-counter shampoos for dandruff and seborrheic dermatitis treatment, and in topical preparations for various dermatological conditions.
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Yes, Pyrithione Zinc is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200471. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 26041. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Медицинский отказ от ответственности
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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