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Simethicone

CHEMBL4297192 Phase 4 Одобрено Unknown
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
238.5 g/mol
LogP
—
Phase
4

Simethicone is an antifoaming agent composed of a mixture of polydimethylsiloxanes and silica gel that reduces surface tension of gas bubbles in the gastrointestinal tract, facilitating their coalescence and expulsion to relieve bloating, flatulence, and gas-associated discomfort. It is pharmacologically inert and not systemically absorbed, acting entirely within the GI lumen. It is widely used as an adjunct in endoscopic procedures to reduce foam interference and as an over-the-counter remedy for gastrointestinal gas.

Молекулярная масса

238,4600 g/mol

TPSA

52,60 Ų

Терапевтические области

Infectious Disease Ovarian Cancer Gastroesophageal Reflux Disease Multiple Sclerosis Chronic Kidney Disease Hypertension Breast Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

SMILES

CO[Si](C)(C)O[Si](C)(C)C.O=[Si]=O

InChI

InChI=1S/C6H18O2Si2.O2Si/c1-7-10(5,6)8-9(2,3)4;1-3-2/h1-6H3;

Molecular Formula

C6H18O4Si3

HBD / HBA

- / 4

Вращаемые Связи

3

Тяжёлые Атомы

13

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Часто задаваемые вопросы

Simethicone is an antifoaming agent composed of a mixture of polydimethylsiloxanes and silica gel that reduces surface tension of gas bubbles in the gastrointestinal tract, facilitating their coalescence and expulsion to relieve bloating, flatulence, and gas-associated discomfort. It is pharmacologically inert and not systemically absorbed, acting entirely within the GI lumen. It is widely used as an adjunct in endoscopic procedures to reduce foam interference and as an over-the-counter remedy for gastrointestinal gas.

Yes, Simethicone is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4297192. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 6433516. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Медицинский отказ от ответственности

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.