💊 Препараты А-Я 🧬 Мишени 🛠 Инструменты 📚 Руководства
Все препараты Классы препаратов Терапевтические области Побочные Эффекты
Руководства Глоссарий Хронология
Сравнения Путешествия препаратов Группы лекарственных средств
🇺🇸 English 🇰🇷 한국어 🇯🇵 日本語 🇨🇳 中文简体 🇪🇸 Español 🇧🇷 Português 🇮🇳 हिन्दी 🇸🇦 العربية 🇫🇷 Français 🇷🇺 Русский 🇩🇪 Deutsch 🇹🇷 Türkçe 🇻🇳 Tiếng Việt 🇮🇩 Bahasa Indonesia 🇹🇭 ไทย

Sulfisomidine

CHEMBL485696 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
278.3 g/mol
LogP
1.2
Phase
4

Sulfisomidine (sulfaisodimidine) is a short-acting sulfonamide antibiotic with good urinary solubility used for urinary tract infections and other susceptible bacterial infections, offering a lower risk of crystalluria than older sulfonamides due to its better aqueous solubility. Like all sulfonamides, it competitively inhibits dihydropteroate synthase to block bacterial folic acid synthesis. Its clinical use has declined with the emergence of sulfonamide resistance.

Молекулярная масса

278,3300 g/mol

LogP

1,20

TPSA

106,00 Ų

Правило пяти Липинского

Соответствует

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
Cc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(C)n1

                

                

                
                

                    
InChI

                    
InChI=1S/C12H14N4O2S/c1-8-7-12(15-9(2)14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)

                

                

                

                    
                    

                        
Molecular Formula

                        
C12H14N4O2S

                    

                    
                    

                        
HBD / HBA

                        
2 / 6

                    

                    
                    

                        
Вращаемые Связи

                        
3

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
19

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
Sulfisomidine (sulfaisodimidine) is a short-acting sulfonamide antibiotic with good urinary solubility used for urinary tract infections and other susceptible bacterial infections, offering a lower risk of crystalluria than older sulfonamides due to its better aqueous solubility. Like all sulfonamides, it competitively inhibits dihydropteroate synthase to block bacterial folic acid synthesis. Its clinical use has declined with the emergence of sulfonamide resistance.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Sulfisomidine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL485696.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5343.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.