Sunitinib Malate

CHEMBL1567 Phase 4 Одобрено Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

532.6 g/mol

LogP

—

Phase

4

A malate form of sunitinib with the same therapeutic properties. A multi-targeted tyrosine kinase inhibitor that blocks several receptors on tumor cells and their blood supply simultaneously, used for kidney cancer, gastrointestinal stromal tumors, and certain pancreatic tumors.

Молекулярная масса

532,6000 g/mol

TPSA

172,00 Å²

Терапевтические области

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Cardiovascular Disease Age-Related Macular Degeneration Respiratory Disease Non-Small Cell Lung Cancer Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Infectious Disease Melanoma Gastroesophageal Reflux Disease Inflammatory Bowel Disease Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Lymphoma Hypertension Breast Cancer Heart Failure Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

SVG PNG

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SMILES

CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C.O=C(O)C[C@H](O)C(=O)O

InChI

InChI=1S/C22H27FN4O2.C4H6O5/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28;5-2(4(8)9)1-3(6)7/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28);2,5H,1H2,(H,6,7)(H,8,9)/b17-12-;/t;2-/m.0/s1

Molecular Formula

C26H33FN4O7

HBD / HBA

6 / 9

Вращаемые Связи

10

Тяжёлые Атомы

38

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Часто задаваемые вопросы

A malate form of sunitinib with the same therapeutic properties. A multi-targeted tyrosine kinase inhibitor that blocks several receptors on tumor cells and their blood supply simultaneously, used for kidney cancer, gastrointestinal stromal tumors, and certain pancreatic tumors.

Yes, Sunitinib Malate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1567. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 6456015. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Структура

Краткие Данные

Формула: C26H33FN4O7
Синонимы: 1

Внешние ссылки

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Медицинский отказ от ответственности

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.