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Talbutal

CHEMBL1200802 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
224.3 g/mol
LogP
1.4
Phase
4

Talbutal is an intermediate-acting barbiturate that acts on GABA-A receptors to enhance chloride ion influx, producing central nervous system depression. It was historically used as a sedative and hypnotic agent for the short-term treatment of insomnia. Due to its high abuse potential, tolerance development, and risk of fatal overdose, it has largely been replaced by safer alternatives.

Молекулярная масса

224,2600 g/mol

LogP

1,40

TPSA

75,30 Ų

Правило пяти Липинского

Соответствует

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
C=CCC1(C(C)CC)C(=O)NC(=O)NC1=O

                

                

                
                

                    
InChI

                    
InChI=1S/C11H16N2O3/c1-4-6-11(7(3)5-2)8(14)12-10(16)13-9(11)15/h4,7H,1,5-6H2,2-3H3,(H2,12,13,14,15,16)

                

                

                

                    
                    

                        
Molecular Formula

                        
C11H16N2O3

                    

                    
                    

                        
HBD / HBA

                        
2 / 3

                    

                    
                    

                        
Вращаемые Связи

                        
4

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
16

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
Talbutal is an intermediate-acting barbiturate that acts on GABA-A receptors to enhance chloride ion influx, producing central nervous system depression. It was historically used as a sedative and hypnotic agent for the short-term treatment of insomnia. Due to its high abuse potential, tolerance development, and risk of fatal overdose, it has largely been replaced by safer alternatives.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Talbutal is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200802.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 8275.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.