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Technetium Sestamibi

CHEMBL6069485 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
— g/mol
LogP
—
Phase
4

Technetium sestamibi (99mTc-MIBI, methoxyisobutylisonitrile) is a lipophilic cationic radiopharmaceutical that accumulates in mitochondria-rich cells proportional to membrane potential, used for myocardial perfusion imaging to evaluate coronary artery disease and assess myocardial viability. It is also used for parathyroid adenoma localization and breast cancer imaging (scintimammography) as a supplement to mammography. The agent's retention in well-perfused, metabolically active myocardium allows distinction of ischemic from infarcted tissue.

Терапевтические области

Ovarian Cancer Thyroid Cancer Non-Small Cell Lung Cancer Type 2 Diabetes Breast Cancer

Механизм действия

Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Механизм

Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Часто задаваемые вопросы

Technetium sestamibi (99mTc-MIBI, methoxyisobutylisonitrile) is a lipophilic cationic radiopharmaceutical that accumulates in mitochondria-rich cells proportional to membrane potential, used for myocardial perfusion imaging to evaluate coronary artery disease and assess myocardial viability. It is also used for parathyroid adenoma localization and breast cancer imaging (scintimammography) as a supplement to mammography. The agent's retention in well-perfused, metabolically active myocardium allows distinction of ischemic from infarcted tissue.

Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.

Yes, Technetium Sestamibi is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL6069485. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

Медицинский отказ от ответственности

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.