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Technetium Tc 99M Mebrofenin

CHEMBL1200421 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
869.3 g/mol
LogP
—
Phase
4

Technetium Tc 99m mebrofenin is a high-efficiency hepatobiliary radiopharmaceutical with superior hepatic extraction for HIDA scintigraphy, particularly valuable in jaundiced patients. See technetium-mebrofenin for complete pharmacological details. It provides high-contrast hepatobiliary imaging for functional and anatomical assessment of the biliary system.

Молекулярная масса

869,3000 g/mol

TPSA

225,00 Ų

Механизм действия

Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Механизм

Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

SMILES

CC1=CC(=C(C(=C1NC(=O)CN(CC(=O)[O-])CC(=O)[O-])C)Br)C.CC1=CC(=C(C(=C1NC(=O)CN(CC(=O)[O-])CC(=O)[O-])C)Br)C.[99Tc+4]

InChI

InChI=1S/2C15H19BrN2O5.Tc/c2*1-8-4-9(2)15(10(3)14(8)16)17-11(19)5-18(6-12(20)21)7-13(22)23;/h2*4H,5-7H2,1-3H3,(H,17,19)(H,20,21)(H,22,23);/q;;+4/p-4/i;;1+1

Molecular Formula

C30H34Br2N4O10Tc

HBD / HBA

2 / 12

Вращаемые Связи

10

Тяжёлые Атомы

47

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Часто задаваемые вопросы

Technetium Tc 99m mebrofenin is a high-efficiency hepatobiliary radiopharmaceutical with superior hepatic extraction for HIDA scintigraphy, particularly valuable in jaundiced patients. See technetium-mebrofenin for complete pharmacological details. It provides high-contrast hepatobiliary imaging for functional and anatomical assessment of the biliary system.

Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

Yes, Technetium Tc 99M Mebrofenin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200421. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 172866200. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Медицинский отказ от ответственности

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.