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Trazodone Hydrochloride

CHEMBL1200798 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
408.3 g/mol
LogP
—
Phase
4

A hydrochloride salt form of trazodone with the same therapeutic properties. This antidepressant medication is prescribed for depression and is widely used off-label to treat insomnia because of its sedating properties.

Молекулярная масса

408,3000 g/mol

TPSA

42,40 Ų

Терапевтические области

Cardiovascular Disease Psychiatry Respiratory Disease Pain Management Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Schizophrenia Generalized Anxiety Disorder Insomnia Infectious Disease Gastroesophageal Reflux Disease Inflammatory Bowel Disease Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Obesity Hypertension Major Depressive Disorder Chronic Pain

Механизм действия

Serotonin antagonist and reuptake inhibitor (SARI).

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Механизм

Serotonin antagonist and reuptake inhibitor (SARI).

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Cl.O=c1n(CCCN2CCN(c3cccc(Cl)c3)CC2)nc2ccccn12

                

                

                
                

                    
InChI

                    
InChI=1S/C19H22ClN5O.ClH/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25;/h1-3,5-7,9,15H,4,8,10-14H2;1H

                

                

                

                    
                    

                        
Molecular Formula

                        
C19H23Cl2N5O

                    

                    
                    

                        
HBD / HBA

                        
1 / 4

                    

                    
                    

                        
Вращаемые Связи

                        
5

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
27

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
A hydrochloride salt form of trazodone with the same therapeutic properties. This antidepressant medication is prescribed for depression and is widely used off-label to treat insomnia because of its sedating properties.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Serotonin antagonist and reuptake inhibitor (SARI).

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Trazodone Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200798.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 62935.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.