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Trihexyphenidyl Hydrochloride

CHEMBL1092 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
337.9 g/mol
LogP
—
Phase
4

Trihexyphenidyl hydrochloride is an anticholinergic agent that blocks muscarinic receptors in the central and peripheral nervous system, reducing excess cholinergic activity. It is primarily used to treat Parkinson's disease and drug-induced extrapyramidal symptoms by restoring dopamine-acetylcholine balance. Its salt form provides improved stability and bioavailability for oral administration.

Молекулярная масса

337,9000 g/mol

TPSA

23,50 Ų

Терапевтические области

Pain Management Schizophrenia Bipolar Disorder Chronic Pain

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

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Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Cl.OC(CCN1CCCCC1)(c1ccccc1)C1CCCCC1

                

                

                
                

                    
InChI

                    
InChI=1S/C20H31NO.ClH/c22-20(18-10-4-1-5-11-18,19-12-6-2-7-13-19)14-17-21-15-8-3-9-16-21;/h1,4-5,10-11,19,22H,2-3,6-9,12-17H2;1H

                

                

                

                    
                    

                        
Molecular Formula

                        
C20H32ClNO

                    

                    
                    

                        
HBD / HBA

                        
2 / 2

                    

                    
                    

                        
Вращаемые Связи

                        
5

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
23

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
Trihexyphenidyl hydrochloride is an anticholinergic agent that blocks muscarinic receptors in the central and peripheral nervous system, reducing excess cholinergic activity. It is primarily used to treat Parkinson's disease and drug-induced extrapyramidal symptoms by restoring dopamine-acetylcholine balance. Its salt form provides improved stability and bioavailability for oral administration.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Trihexyphenidyl Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1092.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 66007.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.