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Umeclidinium

CHEMBL1187833 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
428.6 g/mol
LogP
4.7
Phase
4

This long-acting anticholinergic bronchodilator is used as a once-daily maintenance treatment for chronic obstructive pulmonary disease (COPD) to keep the airways open and relieve shortness of breath. It works by blocking muscarinic receptors in the airway smooth muscle, causing sustained relaxation and widening of the bronchial tubes. It is delivered via a dry powder inhaler and is not intended for use as a rescue medication during sudden breathing difficulties.

Молекулярная масса

428,6000 g/mol

LogP

4,70

TPSA

29,50 Ų

Правило пяти Липинского

Соответствует

Терапевтические области

Asthma Chronic Obstructive Pulmonary Disease Heart Failure

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

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SMILES

                    
OC(c1ccccc1)(c1ccccc1)C12CC[N+](CCOCc3ccccc3)(CC1)CC2

                

                

                
                

                    
InChI

                    
InChI=1S/C29H34NO2/c31-29(26-12-6-2-7-13-26,27-14-8-3-9-15-27)28-16-19-30(20-17-28,21-18-28)22-23-32-24-25-10-4-1-5-11-25/h1-15,31H,16-24H2/q+1

                

                

                

                    
                    

                        
Molecular Formula

                        
C29H34NO2+

                    

                    
                    

                        
HBD / HBA

                        
1 / 2

                    

                    
                    

                        
Вращаемые Связи

                        
8

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
32

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
This long-acting anticholinergic bronchodilator is used as a once-daily maintenance treatment for chronic obstructive pulmonary disease (COPD) to keep the airways open and relieve shortness of breath. It works by blocking muscarinic receptors in the airway smooth muscle, causing sustained relaxation and widening of the bronchial tubes. It is delivered via a dry powder inhaler and is not intended for use as a rescue medication during sudden breathing difficulties.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Umeclidinium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1187833.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 11519070.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.