Verapamil
This calcium channel blocker is used to treat high blood pressure, certain heart rhythm disorders (including atrial fibrillation and supraventricular tachycardia), and angina (chest pain), and is also used to prevent migraine headaches and cluster headaches. It works by slowing the movement of calcium into heart and blood vessel muscle cells, causing the heart to beat more slowly and blood vessels to relax. It interacts with many medications, and grapefruit juice can increase its blood levels significantly.
Молекулярная масса
454,6000 g/mol
LogP
3,80
TPSA
64,00 Ų
Правило пяти Липинского
Соответствует
Терапевтические области
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D Структура
Cite this structure
Embed this structure
SMILES
COc1ccc(CCN(C)CCCC(C#N)(c2ccc(OC)c(OC)c2)C(C)C)cc1OC
InChI
InChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3
Molecular Formula
C27H38N2O4
HBD / HBA
- / 6
Вращаемые Связи
13
Тяжёлые Атомы
33
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Часто задаваемые вопросы
This calcium channel blocker is used to treat high blood pressure, certain heart rhythm disorders (including atrial fibrillation and supraventricular tachycardia), and angina (chest pain), and is also used to prevent migraine headaches and cluster headaches. It works by slowing the movement of calcium into heart and blood vessel muscle cells, causing the heart to beat more slowly and blood vessels to relax. It interacts with many medications, and grapefruit juice can increase its blood levels significantly.
Yes, Verapamil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL6966. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 2520. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Медицинский отказ от ответственности
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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